The irritable male syndrome (IMS) is a behavioural state of nervousness,
irritability, lethargy and depression that occurs in adult male mammals
following withdrawal of testosterone (T). The negative mood state has
been described in men following withdrawal of androgens and is a
striking feature in male seasonally breeding mammals associated with the
end of the mating season.
IMS in humans
In humans, irritable male syndrome is referred to as the andropause,
Andropause: The Male Menopause
Andropause, also known as the male menopause, is
the result of a gradual drop in testosterone and DHEA which
are androgens, giving the condition its name. When men get into
their early 30s, they begin to gradually start decreasing testosterone
levels at a rate of one to two percent a year. It is estimated
approximately 4-5 million men have symptoms of low/low-normal
testosterone levels and only 5-10% of these men will seek
treatment.
Based on World Health Organization (WHO) data,
it was found that the testosterone levels in most 70 year old
men were 10 percent of the level in males in their early 20s.
By early 40s, men can start experiencing symptoms of andropause.
The symptoms of andropause (Irritable Male Syndrome):
- • Weight gain
- • Sleep apnea
- • Memory loss
- • Diminished libido
- • Erectile dysfunction
- • Muscle loss
- • Depression
- • Fatigue
Treatment Options
The following treatments have been found to be effective.
- Hormone replacement therapy
- Exercise, dietary changes, stress reduction
- Selective androgen receptor modulators.
Avoiding Irritable Male Syndrome
In order to help balance
hormone levels and avoid irritable male syndrome, men should try to eat a
well-balanced diet. Men should try to breakdown their diet in the
following manner to help balance their hormone cycle:
- 25 percent fat
- 35 percent low glycemic carbohydrates (carbohydrates that are digested slowly and that do not cause insulin levels to spike)
- 40 percent protein.
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